rs12435797 - NUMB

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide association study of multisite chronic pain in UK Biobank - Unknown journal (n.d.) · Unknown authors · PubMed 31194737

  ABSTRACT: Chronic pain is highly prevalent worldwide and represents a significant socioeconomic and public health burden. Several aspects of chronic pain, for example back pain and a severity-related phenotype 'chronic pain grade', have been shown previously to be complex heritable traits with a polygenic component. Additional pain-related phenotypes capturing aspects of an individual's overall sensitivity to experiencing and reporting chronic pain have also been suggested as a focus for investigation. We made use of a measure of the number of sites of chronic pain in individuals within the UK general population. This measure, termed Multisite Chronic Pain (MCP), is a complex trait and its genetic architecture has not previously been investigated. To address this, we carried out a la

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