rs12426427 - SOX5

Magnitude 4.5 · 1 study on file

Reported associations

  • Nightmares share genetic risk factors with sleep and psychiatric traits - Unknown journal (n.d.) · Unknown authors · PubMed 38413574

    ABSTRACT: Nightmares are vivid, extended, and emotionally negative or negative dreams that awaken the dreamer. While sporadic nightmares and bad dreams are common and generally harmless, frequent nightmares often reflect underlying pathologies of emotional regulation. Indeed, insomnia, depression, anxiety, or alcohol use have been associated with nightmares in epidemiological and clinical studies. However, the connection between nightmares and their comorbidities are poorly understood. Our goal was to examine the genetic risk factors for nightmares and estimate correlation or causality between nightmares and comorbidities. We performed a genome-wide association study (GWAS) in 45,255 individuals using a questionnaire-based assessment on the frequency of nightmares during the past month and


Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.

Lifestyle context

Concrete actions anchored to the cited research. We do not prescribe, we describe.

Lifestyle

  • nightmare frequency and sleep quality Moderate

    SOX5 variants associate with increased nightmare frequency in large genome-wide association study

    track dreams and nightmares weekly; discuss patterns with sleep specialist if concerning