rs12415800 - RNU6-523P - RPL12P8

Magnitude 4.5 · 1 study on file

Reported associations

• Molecular genetic analysis subdivided by adversity exposure suggests etiologic heterogeneity in major depression - Unknown journal (n.d.) · Unknown authors · PubMed 29495898

  ABSTRACT: Objective The extent to which major depression is the outcome of a single biological mechanism or represents a final common pathway of multiple disease processes remains uncertain. Genetic approaches can potentially identify etiologic heterogeneity in major depression by dividing patients on their experience of major adverse events. Method Data are from China, Oxford, and VCU Experimental Research on Genetic Epidemiology (CONVERGE), a study of Han Chinese women with recurrent major depression aimed at identifying genetic risk factors for major depression in a rigorously ascertained cohort carefully assessed for key environmental risk factors (n = 9599). To detect etiologic heterogeneity, genome-wide association studies (GWAS), heritability analyses, and gene-by-environment intera

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.