rs12411769 - RPS26P39 - LINC02641

Magnitude 4.5 · 1 study on file

Reported associations

• Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder - a meta-analysis of genetic studies - Unknown journal (n.d.) · Unknown authors · PubMed 25562672

  ABSTRACT: Objective To test common genetic variants for association with seasonality (seasonal changes in mood and behavior) and to investigate whether there are shared genetic risk factors between psychiatric disorders and seasonality. Methods A meta-analysis of genome-wide association studies (GWAS) conducted in Australian and Amish populations in whom the Seasonal Pattern Assessment Questionnaire (SPAQ) had been administered. The total sample size was 4,156 individuals. Genetic risk scores based on results from prior large GWAS studies of bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ) were calculated to test for overlap in risk between psychiatric disorders and seasonality. Results The most significant association was with rs11825064 (p = 1.7 × 10−6,

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