rs1240783 - LINC02702 - BUD13
Magnitude 2.2 · 1 study on file
Reported associations
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A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population - Unknown journal (n.d.) · Unknown authors · PubMed 38201907
ABSTRACT: The purpose of this study was to investigate genetic factors associated with metabolic syndrome (MetS) by conducting a large-scale genome-wide association study (GWAS) in Taiwan, addressing the limited data on Asian populations compared to Western populations. Using data from the Taiwan Biobank, comprehensive clinical and genetic information from 107,230 Taiwanese individuals was analyzed. Genotyping data from the TWB1.0 and TWB2.0 chips, including over 650,000 single nucleotide polymorphisms (SNPs), were utilized. Genotype imputation using the 1000 Genomes Project was performed, resulting in more than 9 million SNPs. MetS was defined based on a modified version of the Adult Treatment Panel III criteria. Among all participants (mean age: 50 years), 23% met the MetS definition. GW
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
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Metabolic disease prevention strategy Moderate
Elevated genetic metabolic syndrome risk may warrant personalized early prevention and lifestyle intervention strategy
Screening
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Annual metabolic syndrome screening High
rs1240783 associates with substantially increased metabolic syndrome risk; early detection enables intervention
Annual fasting glucose, lipid panel (total, triglycerides, HDL), blood pressure, waist circumference