rs1237669 - MPP3 - CD300LG

Magnitude 2.2 · 1 study on file

Reported associations

• A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry - Unknown journal (n.d.) · Unknown authors · PubMed 37559094

  ABSTRACT: Background Genome-wide studies of gene-environment interactions (G×E) may identify variants associated with disease risk in conjunction with lifestyle/environmental exposures. We conducted a genome-wide G×E analysis of ~ 7.6 million common variants and seven lifestyle/environmental risk factors for breast cancer risk overall and for estrogen receptor positive (ER +) breast cancer. Methods Analyses were conducted using 72,285 breast cancer cases and 80,354 controls of European ancestry from the Breast Cancer Association Consortium. Gene-environment interactions were evaluated using standard unconditional logistic regression models and likelihood ratio tests for breast cancer risk overall and for ER + breast cancer. Bayesian False Discovery Probability was employed

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