rs12363906 - U6 - LINC02711

Magnitude 2.2 · 1 study on file

Reported associations

• Identification of five genetic variants with differential effects on obesity-related traits based on age - Unknown journal (n.d.) · Unknown authors · PubMed 36276968

  ABSTRACT: Obesity is a major public health concern, and its prevalence generally increases with age. As the number of elderly people is increasing in the aging population, the age-dependent increase in obesity has raised interest in the underlying mechanism. To understand the genetic basis of age-related increase in obesity, we identified genetic variants showing age-dependent differential effects on obesity. We conducted stratified analyses between young and old groups using genome-wide association studies of 355,335 United Kingom Biobank participants for five obesity-related phenotypes, including body mass index, body fat percentage, waist-hip ratio, waist circumference, and hip circumference. Using t-statistic, we identified five significant lead single nucleotide polymorphisms: rs22584

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