rs12322558 - BEST3

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide Association Analysis of Longitudinal Bone Mineral Content Data from the Iowa Bone Development Study - Unknown journal (n.d.) · Unknown authors · PubMed 31668963

  ABSTRACT: The foundation for osteoporosis risk is, in part, established during childhood, adolescence, and young adulthood, all periods of development when bone mass is acquired rapidly. The relative quantity of bone mass accrued is influenced by both lifestyle and genetic factors, although the genetic component is not yet well understood. The purpose of this study was to use a genome-wide association (GWA) analysis to discover single nucleotide polymorphisms (SNPs) associated with: (1) the sex-specific hip bone mineral content (BMC) at approximately the age of 19 when the amount of bone accrued is near its peak; and (2) the sex-specific rate of hip BMC accrual during the adolescent growth spurt. The Iowa Bone Development Study, a longitudinal cohort study exploring bone health in children

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