rs12253482 - GLUD1P3

Magnitude 2.2 · 1 study on file

Reported associations

• Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders - Unknown journal (n.d.) · Unknown authors · PubMed 39301620

  ABSTRACT: Aims Anxiety disorders are prevalent and anxiety symptoms (ANX) co‐occur with many psychiatric disorders. We aimed to identify genomic loci associated with ANX, characterize its genetic architecture, and genetic overlap with psychiatric disorders. Methods We included a genome‐wide association study of ANX (meta‐analysis of UK Biobank and Million Veterans Program, n = 301,732), schizophrenia (SCZ), bipolar disorder (BIP), major depression (MD), attention‐deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD), and validated the findings in the Norwegian Mother, Father, and Child Cohort (n = 95,841). We employed the bivariate causal mixture model and local analysis of covariant association to characterize the genetic architecture including overlap

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