rs12133739 - PAPPA2; PAPPA2

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery - BMJ open (2016) · Kertai MD, Li YJ, Li YW, Ji Y, Alexander J, Newman MF, Smith PK, Joseph D, Mathew JP, Podgoreanu MV · PubMed 25948407

  ABSTRACT: Objectives Identification of patient subpopulations susceptible to develop myocardial infarction (MI) or, conversely, those displaying either intrinsic cardioprotective phenotypes or highly responsive to protective interventions remain high-priority knowledge gaps. We sought to identify novel common genetic variants associated with perioperative MI in patients undergoing coronary artery bypass grafting using genome-wide association methodology. Setting 107 secondary and tertiary cardiac surgery centres across the USA. Participants We conducted a stage I genome-wide association study (GWAS) in 1433 ethnically diverse patients of both genders (112 cases/1321 controls) from the Genetics of Myocardial Adverse Outcomes and Graft Failure (GeneMAGIC) study, and a stage II analysis in an

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