rs12126348 - LINC02770 - RGS18

Magnitude 2.2 · 1 study on file

Reported associations

• A genome-wide investigation of food addiction - Unknown journal (n.d.) · Unknown authors · PubMed 27106561

  ABSTRACT: Objective Evidence of parallels between drug addiction and eating behavior continues to accumulate. Genetic studies of addictive substances have yielded a number of susceptibility loci that point to common higher-order genetic pathways underlying addiction. We hypothesized that a genome-wide association study (GWAS) of food addiction would yield significant enrichment in genes and pathways linked to addiction. Methods We conducted a GWAS of food addiction, determined by the modified Yale Food Addiction Scale (mYFAS), among 9,314 women of European ancestry and examined results for enrichment of single-nucleotide polymorphisms (SNPs)(n=44), genes (n=238) and pathways (n=11) implicated in drug addiction. Results Two loci met GW-significance (P<2.5×10−8) mapping to 17q21.31 and 11

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