rs1208134 - CCDC181

Magnitude 2.0 · 1 study on file

Reported associations

• An assessment of the effect of the genotype on postoperative venous thromboembolism risk in 140,831 surgical patients - Annals of medicine and surgery (2012) (2025) · A Christensen M, Bonde A, Sillesen M · PubMed 34777790

  ABSTRACT: Background Postoperative Venous Thromboembolism Events (VTE) constitute a major source of morbidity and mortality after surgery. The aim of this study was to investigate whether commonly occurring Single Nucleotide Polymorphisms (SNPs) are associated with VTE in the surgical setting. Methods Retrospective study using data from the United Kingdom (UK) biobank, a genome biobank containing healthcare and genotyping data from more than 500.000 individuals. A cohort of 140,831patients with a registered surgical procedure was identified and used for a discovery genome wide association study (GWAS), with the remainder of the cohort (305,349 non-surgical patients) used as a replication cohort. Primary outcome was associations between SNPs and VTE within 30 days after a surgical procedure

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