rs12073359 - OTUD7B - RPL6P31

Magnitude 4.5 · 1 study on file

Reported associations

• Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: a report from the St. Jude Lifetime cohort - Unknown journal (n.d.) · Unknown authors · PubMed 25963547

  ABSTRACT: Purpose We aimed to identify treatment and genetic factors associated with obesity among childhood cancer survivors. Methods Participants included 1996 survivors previously treated for cancer at St. Jude Children's Research Hospital who survived ≥10 years from diagnosis (median age at diagnosis 7.2 years, median age at follow-up 32.4 years). Obesity was defined as a body mass index ≥30kg/m2. Factors associated with adult obesity were identified by subgroup-specific (cranial radiation (CRT) exposure status) multivariable logistic regression. Single nucleotide polymorphisms (SNPs) associated with obesity were identified by subgroup-specific exploratory genome-wide association analyses (two-stage resampling approach with type I error rate=5×10−6). Results Forty-seven percen

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