rs12049330 - ATXN7L2

Magnitude 2.8 · 1 study on file

Reported associations

  • Genome-wide association study of recurrent early-onset major depressive disorder - Unknown journal (n.d.) · Unknown authors · PubMed 20125088

    ABSTRACT: A genome-wide association study was carried out in 1,020 case subjects with recurrent early-onset major depressive disorder (MDD) (onset before age 31) and 1,636 control subjects screened to exclude lifetime MDD. Subjects were genotyped with the Affymetrix 6.0 platform. After extensive quality control procedures, 671,424 autosomal SNPs and 25,068 X chromosome SNPs with minor allele frequency greater than 1% were available for analysis. An additional 1,892,186 HapMap II SNPs were analyzed based on imputed genotypic data. Single-SNP logistic regression trend tests were computed, with correction for ancestry-informative principal component scores. No genome-wide significant evidence for association was observed, assuming that nominal P < 5 × 10−8 approximates a 5% genome-wide sig


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