rs12035879 - RGS5-AS1, RGS5

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-Wide Association Study of Liver Enzymes in Korean Children - Unknown journal (n.d.) · Unknown authors · PubMed 24124411

  ABSTRACT: Liver enzyme elevations, as an indicator of liver function, are widely associated with metabolic diseases. Genome-wide population-based association studies have identified a genetic susceptibility to liver enzyme elevations and their related traits; however, the genetic architecture in childhood remains largely unknown. We performed a genome-wide association study to identify new genetic loci for liver enzyme levels in a Korean childhood cohort (n = 484). We observed three novel loci (rs4949718, rs80311637, and rs596406) that were multiply associated with elevated levels of alanine transaminase and aspartate transaminase. Although there are some limitations, including genetic power, additional replication and functional characterization will support the clarity on the genetic con

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