rs12020569 - RPS21P8 - RPS20P32

Magnitude 2.0 · 1 study on file

Reported associations

• Association Analysis of Symptoms of Alcohol Dependence in the Molecular Genetics of Schizophrenia (MGS2) Control Sample - Alcoholism, clinical and experimental research (2012) · Kendler KS, Kalsi G, Holmans PA, Sanders AR, Aggen SH, Dick DM, Aliev F, Shi J, Levinson DF, Gejman PV · PubMed 21314694

  ABSTRACT: Background While genetic influences on Alcohol Dependence (AD) are substantial, progress in the identification of individual genetic variants that impact on risk has been difficult. Methods We performed a genome-wide association study on 3,169 alcohol consuming subjects from the population-based Molecular Genetics of Schizophrenia (MGS2) control sample. Subjects were asked 7 questions about symptoms of AD which were analyzed by confirmatory factor analysis. Genotyping was performed using the Affymetrix 6.0 array. Three sets of analyses were conducted separately for European American (EA, n=2,357) and African-American (AA, n=812) subjects: individual SNPs, candidate genes and enriched pathways using Gene Ontology (GO) categories. Results The symptoms of AD formed a highly coherent

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