rs11995662 - PDGFRL

Magnitude 4.5 · 1 study on file

Reported associations

• Genetic Variations and Risk of Placental Abruption: A Genome-Wide Association Study and Meta-analysis of Genome-Wide Association Studies - Unknown journal (n.d.) · Unknown authors · PubMed 29884306

  ABSTRACT: Introduction Accumulating epidemiological evidence points to strong genetic susceptibility to placental abruption (PA). However, characterization of genes associated with PA remains incomplete. We conducted a genome-wide association study (GWAS) of PA and a meta-analysis of GWAS. Methods Participants of the Placental Abruption Genetic Epidemiology (PAGE) study, a population based case-control study of PA conducted in Lima, Peru, were genotyped using the Illumina HumanCore-24 BeadChip platform. Genotypes were imputed using the 1000 genomes reference panel, and >4.9 million SNPs that passed quality control were analyzed. We performed a GWAS in PAGE participants (507 PA cases and 1,090 controls) and a GWAS meta-analysis in 2,512 participants (959 PA cases and 1,553 controls) that in

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