rs11983060 - THSD7A

Magnitude 2.2 · 1 study on file

Reported associations

• Comparison of Genome-Wide Association Scans for Quantitative and Observational Measures of Human Hair Curvature. - Twin research and human genetics : the official journal of the International Society for Twin Studies (2021) · Ho YYW, Mina-Vargas A, Zhu G, Brims M, McNevin D, Montgomery GW, Martin NG, Medland SE, Painter JN · PubMed 33190678

  Previous genetic studies on hair morphology focused on the overall morphology of the hair using data collected by self-report or researcher observation. Here, we present the first genome-wide association study (GWAS) of a micro-level quantitative measure of hair curvature. We compare these results to GWAS results obtained using a macro-level classification of observable hair curvature performed in the same sample of twins and siblings of European descent. Observational data were collected by trained observers, while quantitative data were acquired using an Optical Fibre Diameter Analyser (OFDA). The GWAS for both the observational and quantitative measures of hair curvature resulted in genome-wide significant signals at chromosome 1q21.3 close to the trichohyalin (TCHH) gene, previously sh

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