rs11974528 - NRCAM

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke - Unknown journal (n.d.) · Unknown authors · PubMed 26674333

  ABSTRACT: Objective: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms. Methods: We first sought to identify genetic associations with white matter hyperintensities in a stroke population, and then examined whether genetic loci previously linked to WMHV in community populations are also associated in stroke patients. Having established that genetic associations are shared between the 2 populations, we performed a meta-analysis testing which associations with WMHV in stroke-free populations are associated overall when combined with stroke populations. Results: Th

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