rs1193394 - TMEM132C

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide Association study of Asthma, Total IgE, and Lung function in a Cohort of Peruvian Children - Unknown journal (n.d.) · Unknown authors · PubMed 33713768

  ABSTRACT: BACKGROUND: Genetic ancestry plays a role in asthma health disparities. OBJECTIVE: To evaluate the impact of ancestry on, and identify genetic variants associated with asthma, serum immunoglobulin E (IgE), and lung function. METHODS: 436 Peruvian children (9-19 years) with asthma and 291 without asthma were genotyped using the Illumina Multi-Ethnic Global Array. Genome-wide proportions of Indigenous ancestry from continental America (NAT) and European ancestry from Iberian Populations in Spain (IBS) were estimated using ADMIXTURE. We assessed the relationship between ancestry and the phenotypes, and performed a genome-wide association study. RESULTS: Mean ancestry was 84.7% NAT (cases: 84.2%; controls: 85.4%) and 15.3% IBS (15.8%; 14.6%). Adjusting for asthma, NAT was associate

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