rs11873030 - MALT1
Magnitude 2.2 · 1 study on file
Reported associations
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The phenotypic and genetic association between endometriosis and immunological diseases - Unknown journal (n.d.) · Unknown authors · PubMed 40262193
ABSTRACT: Abstract STUDY QUESTION Is there an increased risk of immunological diseases among endometriosis patients, and does a shared genetic basis contribute to this risk? SUMMARY ANSWER Endometriosis patients show a significantly increased risk of autoimmune, autoinflammatory, and mixed-pattern diseases, including rheumatoid arthritis, multiple sclerosis, coeliac disease, osteoarthritis, and psoriasis, with genetic correlations between endometriosis and osteoarthritis, rheumatoid arthritis, and multiple sclerosis, and a potential causal link to rheumatoid arthritis. WHAT IS KNOWN ALREADY The epidemiological evidence for an increased risk of immunological diseases among women with endometriosis is limited in scope and has varied in robustness due to the opportunity for biases. The presen
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
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neurological baseline and MS risk assessment Moderate
rs11873030-C allele increases multiple sclerosis risk in large European cohort; MALT1 protein regulates immune T cell signaling.
Neurological exam and baseline MRI if symptomatic or strong family history