rs11864333 - RMI2 - LITAF

Magnitude 2.0 · 1 study on file

Reported associations

• Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors - Unknown journal (n.d.) · Unknown authors · PubMed 26920376

  ABSTRACT: Background Epidemiological findings suggest a relationship between multiple sclerosis (MS) and cardiovascular disease (CVD) risk factors, although the nature of this relationship is not well understood. Objective We used genome-wide association study (GWAS) data to identify shared genetic factors (pleiotropy) between MS and CVD risk factors. Methods Using summary statistics from large, recent GWAS (total n > 250,000 individuals), we investigated overlap in single nucleotide polymorphisms (SNPs) associated with MS and a number of CVD risk factors including triglycerides (TG), low density lipoproteins cholesterol (LDL), high density lipoproteins cholesterol (HDL), body mass index, waist-hip-ratio, type 2 diabetes, systolic blood pressure and C-reactive protein level. Results and Co

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