rs11839439 - RNU6-66P - RNU4-10P

Magnitude 2.8 · 1 study on file

Reported associations

• Genetic susceptibility to prostate cancer in Taiwan: A genome-wide association study. - Molecular carcinogenesis (2024) · Bau DT, Tsai CW, Chang WS, Yang JS, Liu TY, Lu HF, Wang YW, Tsai FJ · PubMed 38390760

  We conducted the first genome-wide association study (GWAS) of prostate cancer (PCa) in Taiwan with 1844 cases and 80,709 controls. Thirteen independent single-nucleotide polymorphisms (SNPs) reached genome-wide significance (p < 5 × 10 ). Among these, three were distinct from previously identified loci: rs76072851 in CORO2B gene (15q23), odds ratio (OR) = 1.54, 95% confidence interval (CI), 1.36-1.76, p = 5.30 × 10 ; rs7837051, near two long noncoding RNA (lncRNA) genes, PRNCR1 and PCAT2 (8q24.21), OR = 1.41 (95% CI, 1.31-1.51), p = 8.77 × 10 ; and rs56339048, near an lncRNA gene, CASC8 (8q24.21), OR = 1.25 (95% CI, 1.16-1.35), p = 2.14 × 10 . We refined the lead SNPs for two previously identified SNPs in Taiwanese: rs13255059 (near CASC8),

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