rs117953624 - PDGFD - LINC02552

Magnitude 4.5 · 1 study on file

Reported associations

• Association of Single-Nucleotide Variants in the Human Leukocyte Antigen and Other Loci With Childhood Hodgkin Lymphoma - Unknown journal (n.d.) · Unknown authors · PubMed 35939300

  ABSTRACT: Key Points Question What genetic variants or genes are associated with the risk of childhood Hodgkin lymphoma? Findings In this genetic association study nested within 3 childhood cancer survivor cohorts, 3 independent single-nucleotide variants (SNVs, formerly single-nucleotide polymorphisms) in the human leukocyte antigen (HLA) locus and 5 loci in non-HLA regions were found to be significantly associated with risk of childhood-onset Hodgkin lymphoma. Two-thirds of previously reported Hodgkin lymphoma-associated non-HLA SNVs were replicated in the analysis. Meaning These findings suggest predominantly common and potentially unique genetic etiology between childhood-onset and adulthood-onset Hodgkin lymphoma. This genetic association study evaluates the association of single-nu

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