rs11795332 - TTC39B - RPL7P33

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association study of handgrip strength in the Northern Chinese adult twins. - Connective tissue research (2023) · Luo J, Zhang T, Wang W, Zhang D · PubMed 35876483

  Currently, new loci related to handgrip strength have been identified in genome-wide association studies. However, this topic is an understudied area in the Chinese population. A total of 135 dizygotic twin pairs recruited from the Qingdao Twin Registry system were included in the present study. Using GEMMA, VEAGSE2, and PASCAL software for SNP-based analysis, gene-based analysis, and pathway-based analysis, respectively. The resulting SNPs were subjected to eQTL analysis. Although none of the loci reach the statistically significant level ( < 5 × 10 ), we found 19 SNPs exceeding the suggestive significant level ( < 1 × 10 ). After imputation, 162 SNPs reached suggestive evidence level for handgrip strength. A total of 1,118 genes reached the nominal significance level ( < 

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