rs117744226 - PELI2

Magnitude 4.5 · 1 study on file

Reported associations

• A Genome-Wide Association Study in Early COPD: Identification of One Major Susceptibility Loci. - International journal of chronic obstructive pulmonary disease (2021) · Lee YJ, Choi S, Kwon SY, Lee Y, Lee JK, Heo EY, Chung HS, Kim DK · PubMed 33235445

  Identifying the genetic basis of airflow limitation is one of the most interesting issues for understanding chronic obstructive pulmonary disease (COPD) pathophysiology. Several studies have shown that some genetic variants associated with COPD have been identified in genome-wide association study (GWAS), especially in patients with moderate to severe COPD; genetic susceptibility for airflow limitation in the early COPD phase has not been widely studied. We investigated the genetic variants in early COPD. The present study analyzed Gene-environment interaction and phenotype (GENIE) cohort that included participants who received health screening examination. The association between single nucleotide polymorphism (SNP) and susceptibility to early COPD (FEV1 predicted ≥50% and FEV1/FVC <0.7

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