rs11773966 - MAPK6P1 - ATP6V1H

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide association of mood-incongruent psychotic bipolar disorder - Unknown journal (n.d.) · Unknown authors · PubMed 23092984

  ABSTRACT: Mood-incongruent psychotic features (MICP) are familial symptoms of bipolar disorder (BP) that also occur in schizophrenia (SZ), and may represent manifestations of shared etiology between the major psychoses. In this study we have analyzed three large samples of BP with imputed genome-wide association data and have performed a meta-analysis of 2196 cases with MICP and 8148 controls. We found several regions with suggestive evidence of association (P<10-6), although no marker met genome-wide significance criteria. The top associations were on chromosomes: 6q14.2 within the PRSS35/SNAP91 gene complex (rs1171113, P=9.67 × 10-8); 3p22.2 downstream of TRANK/LBA1 (rs9834970, P=9.71 × 10-8); and 14q24.2 in an intron of NUMB (rs2333194, P=7.03 × 10-7). These associations were

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