rs11761231 - EEF1B2P6 - NDUFB9P2

Magnitude 2.8 · 1 study on file

Reported associations

• Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls - Unknown journal (n.d.) · Unknown authors · PubMed 17554300

  ABSTRACT: There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix GeneChip 500K Mapping Array Set) undertaken in the British population, which has examined ~2,000 individuals for each of 7 major diseases and a shared set of ~3,000 controls. Case-control comparisons identified 24 independent association signals at P<5×10-7: 1 in bipolar disorder, 1 in coronary artery disease, 9 in Crohn's disease, 3 in rheumatoid arthritis, 7 in type 1 diabetes and 3 in type 2 diabetes. On the basis of prior findings and replication studies thus-far completed, almost all of these signals reflect genuine susceptibility effects. We observed asso

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