rs1175802 - TRPM4

Magnitude 2.0 · 1 study on file

Reported associations

• Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women - mSystems (2021) · Fan W, Kan H, Liu HY, Wang TL, He YN, Zhang M, Li YX, Li YJ, Meng W, Li Q, Hu AQ, Zheng YJ · PubMed 34282934

  ABSTRACT: ABSTRACT The influence of human genetic variants on the vaginal bacterial traits (VBTs) of pregnant women is still unknown. Using a genome-wide association approach based on the 16S rRNA bacteriome analysis, a total of 72 host genetic variant (single nucleotide polymorphisms [SNPs], indels, or copy number variations [CNVs])-VBT associations were found that reached the genome-wide significance level (P < 5 × 10−8) with an acceptable genomic inflation factor λ of <1.1. The majority of these SNPs that reached the genome-wide significance level had a relatively low minor allele frequency (MAF), and only seven of them had MAFs greater than 0.05. rs303212, located at the IFIT1 gene on chromosome 10, was the most eye-catching variant, which had a genome-wide association with

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.