rs117180252 - HMHB1 - RN7SL87P
Magnitude 2.2 · 1 study on file
Reported associations
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Polymorphism rs10105606 of LPL as a Novel Risk Factor for Microalbuminuria - Unknown journal (n.d.) · Unknown authors · PubMed 34934334
ABSTRACT: Introduction An important clinical feature of metabolic syndrome is abdominal obesity. Microalbuminuria is important in predicting the risk of cardiovascular and renal complications in abdominal obesity patients. However, the association between microalbuminuria polymorphism and abdominal obesity has not been conducted. The objective of this study is to analyze the genetic polymorphism of microalbuminuria in participants with metabolically unhealthy obesity (MUO). Methods Among 1325 MUO participants, we identified genomic loci underlying those with microalbuminuria, compared to those without microalbuminuria. Single nucleotide polymorphisms (SNPs) were selected with P < 1 × 10−5 from the Manhattan plot. Multivariable linear regression and analysis of variance were used to anal
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Screening
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microalbuminuria status Moderate
The T allele of rs117180252 is associated with 2-fold increased microalbuminuria risk in metabolically unhealthy obese individuals
Annual urine albumin-to-creatinine ratio (ACR) if carrying T allele