rs117149102 - SLCO1B7, SLCO1B3-SLCO1B7

Magnitude 4.5 · 1 study on file

Reported associations

• Genetic association study identifies genetic variants for non-alcoholic fatty liver without comorbidities in the Korean population. - Genes & genomics (2023) · Kim YJ, Cho YS · PubMed 37133724

  Non-alcoholic fatty liver (NAFL) refers to a disease in which fat builds up in the liver, similar to what occurs for those who drink a lot of alcohol, even in cases of not drinking alcohol at all or only in a small amount. Along with non-alcoholic steatohepatitis (NASH), NAFL is a type of non-alcoholic fatty liver disease (NAFLD). Currently, the prevalence of NAFLD is increasing worldwide. A wide range of comorbidities that can increase the risk of NAFLD includes obesity, type 2 diabetes, dyslipidemia, and metabolic syndrome. This study aimed to discover genetic variants for NAFL in the Korean population. Differing from previous studies, we conducted a genome-wide association study for NAFL in the selected subjects without comorbidities to rule out bias due to the inclusion of confounding

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