rs117084279 - PIBF1

Magnitude 2.8 · 1 study on file

Reported associations

• A genome-wide association study of quantitative computed tomographic emphysema in Korean populations - Unknown journal (n.d.) · Unknown authors · PubMed 34404834

  ABSTRACT: Emphysema is an important feature of chronic obstructive pulmonary disease (COPD). Genetic factors likely affect emphysema pathogenesis, but this question has predominantly been studied in those of European ancestry. In this study, we sought to determine genetic components of emphysema severity and characterize the potential function of the associated loci in Korean population. We performed a genome-wide association study (GWAS) on quantitative emphysema in subjects with or without COPD from two Korean COPD cohorts. We investigated the functional consequences of the loci using epigenetic annotation and gene expression data. We also compared our GWAS results with an epigenome-wide association study and previous differential gene expression analysis. In total, 548 subjects (476 [86

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