rs117074522 - CYP4F24P

Magnitude 2.2 · 1 study on file

Reported associations

• A genome-wide association study identifies a possible role for cannabinoid signalling in the pathogenesis of diabetic kidney disease - Unknown journal (n.d.) · Unknown authors · PubMed 36949158

  ABSTRACT: Diabetic kidney disease (DKD), also known as diabetic nephropathy, is the leading cause of renal impairment and end-stage renal disease. Patients with diabetes are at risk for DKD because of poor control of their blood glucose, as well as nonmodifiable risk factors including age, ethnicity, and genetics. This genome-wide association study (GWAS) was conducted for the first time in the Emirati population to investigate possible genetic factors associated with the development and progression of DKD. We included data on 7,921,925 single nucleotide polymorphism (SNPs) in 258 cases of type 2 diabetes mellitus (T2DM) who developed DKD and 938 control subjects with T2DM who did not develop DKD. GWAS suggestive results (P < 1 × 10-5) were further replicated using summary stati

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