rs116995833 - LINC00430 - UBBP5
Magnitude 2.2 · 1 study on file
Reported associations
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Associations between electronic devices use and common mental traits: A gene-environment interaction model using the UK Biobank data. - Addiction biology (2022) · Ye J, Cheng S, Chu X, Wen Y, Cheng B, Liu L, Liang C, Kafle OP, Jia Y, Wu C, Wang S, Wang X, Ning Y, Zhang F · PubMed 34877740
Electronic devices use has been reported to be associated with depression. However, limited effort has been provided to elucidate the associations between electronic devices use and mental traits in interaction with genetic factors. We first conducted an observational study consisting of 138 976-383 742 participants for TV watching, 29 636-38 599 participants for computer using and 118 61-330 985 participants for computer playing in the UK Biobank cohort. A linear regression model was used to evaluate the associations between common mental traits and electronic devices use. Subsequently, a genome-wide gene-environment interaction study (GWEIS) was performed by PLINK2.0 to estimate the interaction effects of genes and electronic devices use on the risks of the four mental traits
Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.
Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Lifestyle
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anxiety levels relative to screen time Moderate
This genetic variant shows a significant interaction where computer use hours and anxiety severity co-elevate, suggesting awareness of this relationship may be beneficial
Track daily screen hours and anxiety symptoms weekly to identify patterns
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reducing daily computer use if anxiety is elevated Moderate
Carrying this variant amplifies the relationship between screen time and anxiety severity, suggesting proactive management may help reduce overall anxiety burden
If experiencing elevated anxiety, aim to reduce daily screen time by 1-2 hours