rs11686759 - PAPOLG

Magnitude 2.2 · 1 study on file

Reported associations

• Interactions between genetic variants and environmental risk factors are associated with the severity of pelvic organ prolapse - Unknown journal (n.d.) · Unknown authors · PubMed 37040585

  ABSTRACT: This study provided preliminary evidence that interactions between genetic variants and environmental risk factors are associated with pelvic organ prolapse severity, suggesting the potential use of combining epidemiologic exposure data with selected genotyping for risk assessment and patient stratification. Abstract Objective Both environmental and genetic risk factors contribute to pelvic organ prolapse (POP). No genome-wide study has investigated the gene-environment (G × E) interactions. In this study, we aim to identify single nucleotide polymorphisms (SNPs) that may interact with the potential environmental factors, maximum birth weight, and age in Chinese women. Methods We recruited 576 women for phase 1 and 264 women for phase 2 with stages III and IV prolapse from six g

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