rs116861740 - MIR99AHG - RNU1-98P

Magnitude 2.0 · 1 study on file

Reported associations

• EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population - Lipids in health and disease (2018) · Kim M, Yoo HJ, Kim M, Kim J, Baek SH, Song M, Lee JH · PubMed 29208002

  ABSTRACT: Background Erythropoietin-producing human hepatocellular (Eph) receptors might contribute to the development of atherosclerosis. A genome-wide association study indicated that the Eph receptor A6 gene (EPHA6) associated with at least 1 blood pressure (BP) phenotype. The objective of the present study was to determine whether EPHA6 is a novel candidate gene for hypertension in a Korean population. Methods A total 2146 study participants with normotension and hypertension were included. Genotype data were obtained using a Korean Chip. To assess the association between single-nucleotide polymorphisms (SNPs) and BP, we performed a linear regression analysis, which showed that rs4850755 in the EPHA6 gene was the SNP most highly associated with both systolic and diastolic BP. Results T

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