rs11662368 - RNU6-567P - LINC03111

Magnitude 4.5 · 1 study on file

Reported associations

  • A Genome-Wide Association Study of Childhood Body Fatness - Unknown journal (n.d.) · Unknown authors · PubMed 33491310

    ABSTRACT: Objective: To uncover genetic contributors to adiposity in early-life. Methods: We conducted a genome-wide association study (GWAS) of childhood body fatness in 34,401 individuals within the Nurses' Health Studies and the Health Professionals Follow-up Study. We imputed using the 1000 Genomes Phase 3 v5 reference panel. Results: We identified 1,354 SNPs (p<10−4) from a previously published GWAS of childhood body mass index (BMI). We observed 19 genome-wide significant (p<5x 10−8) regions, of which 14 were previously associated with childhood obesity, while five were novel: BNDF (p= 7.58 x 10−13), PRKD1 (p= 1.43 x10−10), 20p13 (p= 2.05 x10−10), FHIT (p= 1.77 x10−08), and LOC101927575 (p=3.22 x 10−08). The BNDF, FHIT and PRKD1 regions were previously associated with


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