rs116620371 - FHOD3

Magnitude 2.0 · 1 study on file

Reported associations

• African Ancestry GWAS of Dementia in a Large Military Cohort Identifies Significant Risk Loci - Unknown journal (n.d.) · Unknown authors · PubMed 36543923

  ABSTRACT: While genome wide association studies (GWASs) of Alzheimer's Disease (AD) in European (EUR) ancestry cohorts have identified approximately 83 potentially independent AD risk loci, progress in non-European populations has lagged. In this study, data from the Million Veteran Program (MVP), a biobank which includes genetic data from more than 650,000 US Veteran participants, was used to examine dementia genetics in an African descent (AFR) cohort. A GWAS of Alzheimer's disease and related dementias (ADRD), an expanded AD phenotype including dementias such as vascular and non-specific dementia that included 4,012 cases and 18,435 controls age 60+ in AFR MVP participants was performed. A proxy dementia GWAS based on survey-reported parental AD or dementia (n=4,385 maternal cases,

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