rs11659841 - CDH2 - ARIH2P1

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-Wide Association Study of Periodontal Health Measured by Probing Depth in Adults Ages 18−49 years - Unknown journal (n.d.) · Unknown authors · PubMed 24347629

  ABSTRACT: The etiology of chronic periodontitis clearly includes a heritable component. Our purpose was to perform a small exploratory genome-wide association study in adults ages 18-49 years to nominate genes associated with periodontal disease−related phenotypes for future consideration. Full-mouth periodontal pocket depth probing was performed on participants (N = 673), with affected status defined as two or more sextants with probing depths of 5.5 mm or greater. Two variations of this phenotype that differed in how missing teeth were treated were used in analysis. More than 1.2 million genetic markers across the genome were genotyped or imputed and tested for genetic association. We identified ten suggestive loci (p-value ≤ 1E-5), including genes/loci that have been previously im

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