rs1165593236 - KSR2

Magnitude 2.2 · 1 study on file

Reported associations

• Genome‑wide association study and polygenic risk scores predict psoriasis and its shared phenotypes in Taiwan - Unknown journal (n.d.) · Unknown authors · PubMed 38757301

  ABSTRACT: Psoriasis is a chronic inflammatory dermatological disease, and there is a lack of understanding of the genetic factors involved in psoriasis in Taiwan. To establish associations between genetic variations and psoriasis, a genome-wide association study was performed in a cohort of 2,248 individuals with psoriasis and 67,440 individuals without psoriasis. Using the ingenuity pathway analysis software, biological networks were constructed. Human leukocyte antigen (HLA) diplotypes and haplotypes were analyzed using Attribute Bagging (HIBAG)-R software and chi-square analysis. The present study aimed to assess the potential risks associated with psoriasis using a polygenic risk score (PRS) analysis. The genetic association between single nucleotide polymorphisms (SNPs) in psoriasis a

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