rs11655160 - TMEM220-AS1 - RN7SL601P

Magnitude 2.2 · 1 study on file

Reported associations

• 17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage - Unknown journal (n.d.) · Unknown authors · PubMed 29915124

  ABSTRACT: Background and Purpose Hematoma volume is an important determinant of clinical outcome in spontaneous intracerebral hemorrhage (ICH). We performed a genome-wide association study (GWAS) of hematoma volume with the aim of identifying novel biological pathways involved in the pathophysiology of primary brain injury in ICH. Methods We conducted a two-stage (discovery and replication) case-only genome-wide association study in ICH patients of European ancestry. We utilized the admission head computed tomography (CT) to calculate hematoma volume via semi-automated computer-assisted technique. After quality control and imputation, seven million genetic variants were available for association testing with ICH volume, which was carried out separately in lobar and non-lobar ICH cases usin

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.