rs116510623 - RNU6-783P - LINC02686

Magnitude 4.5 · 1 study on file

Reported associations

• Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study - Unknown journal (n.d.) · Unknown authors · PubMed 31178898

  ABSTRACT: Background Chronic kidney disease (CKD) is common and disproportionally burdens United States ethnic minorities. Its genetic determinants may differ by disease severity and clinical stages. To uncover genetic factors associated CKD severity among high-risk ethnic groups, we performed genome-wide association studies (GWAS) in diverse populations within the Population Architecture using Genomics and Epidemiology (PAGE) study. Methods We assembled multi-ethnic genome-wide imputed data on CKD non-overlapping cases [4,150 mild to moderate CKD, 1,105 end-stage kidney disease (ESKD)] and non-CKD controls for up to 41,041 PAGE participants (African Americans, Hispanics/Latinos, East Asian, Native Hawaiian, and American Indians). We implemented a generalized estimating equation approach f

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