rs11645661 - ACSM2B

Magnitude 2.2 · 1 study on file

Reported associations

• Genome‐wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci - Unknown journal (n.d.) · Unknown authors · PubMed 33634981

  [INTRO] Dear Editor, [INTRO] We performed a metabolome‐based genome‐wide association study (metaboGWAS) in a Chinese cohort with coronary artery disease (CAD). We identified seven novel metabolite quantitative trait loci (metaboQTLs) and revealed the possible clinical significance of these metaboQTLs. Our study may add novel biological insights into the metabolic background of disease‐related variants and contribute to the development of risk prediction and treatment of CAD. [INTRO] CAD is the most common type of cardiovascular disease worldwide, with high morbidity and mortality. 1 To date, genetic variants can explain approximately 10.6% of CAD heritability, 2 whereas the internal biological information is often limited. Plasma metabolites represent a functional intermediate fo

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