rs1163656 - ACSS3

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association Scan of dental caries in the permanent dentition - Unknown journal (n.d.) · Unknown authors · PubMed 23259602

  ABSTRACT: Background Over 90% of adults aged 20 years or older with permanent teeth have suffered from dental caries leading to pain, infection, or even tooth loss. Although caries prevalence has decreased over the past decade, there are still about 23% of dentate adults who have untreated carious lesions in the US. Dental caries is a complex disorder affected by both individual susceptibility and environmental factors. Approximately 35-55% of caries phenotypic variation in the permanent dentition is attributable to genes, though few specific caries genes have been identified. Therefore, we conducted the first genome-wide association study (GWAS) to identify genes affecting susceptibility to caries in adults. Methods Five independent cohorts were included in this study, totaling more than

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