rs11635868 - STRA6

Magnitude 2.0 · 1 study on file

Reported associations

• Hierarchical Investigation of Genetic Influences on Response Inhibition in Healthy Young Adults - Unknown journal (n.d.) · Unknown authors · PubMed 29251981

  ABSTRACT: Poor inhibitory control is a known risk factor for substance use disorders, making it a priority to identify the determinants of these deficits. The aim of the current study was to identify genetic associations with inhibitory control using the stop signal task in a large sample (n=934) of healthy young adults of European ancestry. We genotyped the subjects genome-wide and then used a hierarchical approach in which we tested: 1) 7 a priori single nucleotide polymorphisms (SNPs) previously associated with stop signal task performance; 2) ~9,000 SNPs designated as high-value addiction (HVA) markers by the SmokeScreen© array; and 3) ~5M genotyped and imputed SNPs, followed by a gene-based association analysis utilizing the resultant p-values. A priori SNP analyses revealed nominall

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