rs11622885 - LINC00609

Magnitude 2.2 · 1 study on file

Reported associations

• Association Between Genetic Risk, Adherence to Healthy Lifestyle Behavior, and Thyroid Cancer Risk - Unknown journal (n.d.) · Unknown authors · PubMed 36508215

  ABSTRACT: Key Points Question Is a healthy lifestyle associated with thyroid cancer risk, and could it attenuate the influence of genetic variants on thyroid cancer? Findings In this cohort study that included 423 patients with incident thyroid cancer and 264 533 individuals without thyroid cancer, adherence to a healthier lifestyle attenuated the negative association of genetic factors with the risk of thyroid cancer in those of European descent. Participants with both a high polygenic risk score and an unfavorable lifestyle had the highest risk of thyroid cancer. Meaning The findings of this study highlight the potential of lifestyle interventions to reduce the risk of thyroid cancer, even in those at high genetic risk. Importance Genetic and lifestyle factors are related to thyroid ca

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