rs116163438 - RPL7L1P21 - EEIG2
Magnitude 2.2 · 1 study on file
Reported associations
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Identifying missing pieces in color vision defects: a genome-wide association study in Silk Road populations - Unknown journal (n.d.) · Unknown authors · PubMed 37359372
ABSTRACT: Introduction: Color vision defects (CVDs) are conditions characterized by the alteration of normal trichromatic vision. CVDs can arise as the result of alterations in three genes (OPN1LW, OPN1MW, OPN1SW) or as a combination of genetic predisposition and environmental factors. To date, apart from Mendelian CVDs forms, nothing is known about multifactorial CVDs forms. Materials and Methods: Five hundred and twenty individuals from Silk Road isolated communities were genotyped and phenotypically characterized for CVDs using the Farnsworth D-15 color test. The CVDs traits Deutan-Protan (DP) and Tritan (TR) were analysed. Genome Wide Association Study for both traits was performed, and results were corrected with a False Discovery Rate linkage-based approach (FDR-p). Gene expression o
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
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Genetic risk for Tritan color vision defects Moderate
Genetic association between rs116163438 and Tritan color defects may have implications for occupational and educational planning
Discuss with ophthalmologist or genetic counselor during routine eye care
Screening
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Tritan color vision screening Moderate
GWAS association indicates increased genetic risk for Tritan (blue-yellow) color vision defects
Request Farnsworth D-15 or similar color vision test from ophthalmologist or optometrist