rs1160544 - LINC01104

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide analysis identifies 12 loci influencing human reproductive behavior - Unknown journal (n.d.) · Unknown authors · PubMed 27798627

  ABSTRACT: The genetic architecture of human reproductive behavior - age at first birth (AFB) and number of children ever born (NEB) - has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric disorders. However, very few genetic loci have been identified and the underlying mechanisms of AFB and NEB are poorly understood. We report the largest genome-wide association study to date of both sexes including 251,151 individuals for AFB and 343,072 for NEB. We identified 12 independent loci that are significantly associated with AFB and/or NEB in a SNP-based genome-wide association study, and four additional loci in a gene-based effort. These loci harbor genes that are likely to play a role - either directly or by affecting non-local gene expressio

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