rs1160133 - LINC03133 - UBXN2B

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-Wide Association Studies of the Human Gut Microbiota - Unknown journal (n.d.) · Unknown authors · PubMed 26528553

  ABSTRACT: The bacterial composition of the human fecal microbiome is influenced by many lifestyle factors, notably diet. It is less clear, however, what role host genetics plays in dictating the composition of bacteria living in the gut. In this study, we examined the association of ~200K host genotypes with the relative abundance of fecal bacterial taxa in a founder population, the Hutterites, during two seasons (n = 91 summer, n = 93 winter, n = 57 individuals collected in both). These individuals live and eat communally, minimizing variation due to environmental exposures, including diet, which could potentially mask small genetic effects. Using a GWAS approach that takes into account the relatedness between subjects, we identified at least 8 bacterial taxa whose abundances were associa

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