rs115997623 - NDST3

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide interaction study of dust mite allergen on lung function in children with asthma - Unknown journal (n.d.) · Unknown authors · PubMed 28167095

  ABSTRACT: Background Childhood asthma is likely the result of gene-by-environment (G×E) interactions. Dust mite is a known risk factor for asthma morbidity. Yet, there have been no genome-wide G×E studies of dust mite allergen on asthma-related phenotypes. Objective To identify genetic variants whose effects on lung function in children with asthma are modified by level of dust mite allergen exposure. Methods A genome-wide interaction analysis of dust mite allergen level and lung function was performed in a cohort of Puerto Rican children with asthma (PRGOAL). Replication was attempted in two independent cohorts, the Childhood Asthma Management Program (CAMP) and the Genetics of Asthma in Costa Rica Study. Results SNP rs117902240 showed a significant interaction with dust mite allergen l

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